Awards / Outstanding Technology Award
Winners
15th 2025
Title:
Development of a method for predicting drug-induced convulsions using machine learning and heart rate variability analysis
Winner:
KUGA Kazuhiro
Affiliation:
Astellas Pharma Inc.
Title:
Development of an in vitro evaluation system for pseudo-allergic reaction using canine and human MRGPRX2-expressing cells
Winner:
HAMAMURA-YASUNO Eri
Affiliation:
Daiichi Sankyo Co., Ltd.
Title:
Optimization and validation of the zebrafish embryo MEFL test method for assessing embryo-fetal developmental toxicity
Winner:
MORI Kanako
Affiliation:
Astellas Pharma Inc.
14th 2024
Title:
Construction of an in vitro-based bile canaliculi model with improved reproducibility
Winner:
KITAGUCHI Takashi
Affiliation:
Global Food Safety Institute, Nissin Foods Holdings Co., Ltd.
Title:
Establishing the versatility of miR-216a and miR-217 as biomarkers of acute pancreatic toxicity
Winner:
KURASHIGE Seiichiro
Affiliation:
EA Pharma Co., Ltd. (Current: Kyowa Kirin Co., Ltd.)
Title:
Efforts to improve extrapolation of in vitro hepatotoxicity assessment systems
Winner:
TAKEMURA Akinori
Affiliation:
Laboratory of Biopharmaceutics, Graduate School of Pharmaceutical Sciences, Chiba University
13th 2023
Title:
Validation of prediction method of addiction-inducing drug based on electrical activity of cultured human iPS cell-derived dopamine neurons
Winner:
ISHIBASHI Yuto
Affiliation:
Graduate School of Engineering, Tohoku Institute of Technology
Title:
Reactive oxygen species (ROS) assay without using DMSO
Winner:
OHTAKE Toshiyuki
Affiliation:
Shiseido Co., Ltd.
Title:
Understanding the drug-induced hepatotoxicity in rats —Involvement of the CYP1A1 inhibition-mediated activation of the aryl hydrocarbon receptor (AHR)—
Winner:
YODA Tomomi
Affiliation:
Preclinical Research Unit, Sumitomo Pharma Co., Ltd.
12th 2022
Title:
Development of cell-based high-throughput screening for the evaluation of reactive metabolite formation potential
Winner:
HARADA Kosuke
Affiliation:
Drug Safety Research & Evaluation, Takeda Pharmaceutical Company Limited
Title:
Detection of acute and chronic cardiotoxicity by imaging-based contractile assay system using human iPS cell-derived cardiomyocytes
Winner:
YANAGIDA Shota
Affiliation:
Division of Pharmacology, National Institute of Health Sciences / Graduated School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
11th 2021
Title:
Approaches to understanding idiosyncratic drug toxicity using human HLA transgenic mice
Winner:
AOKI Shigeki
Affiliation:
Laboratory of Biopharmaceutics, Graduate School of Pharmaceutical Sciences, Chiba University
Title:
Establishment of a new risk assessment method for skin sensitization by applying the dermal sensitization threshold
Winner:
NISHIJO Taku
Affiliation:
Safety Science Research Laboratories, Kao Corporation
10th 2020
Title:
Human iPS cell-derived mast cells useful for in vitro mast cell activation assay exhibiting phenotypes and morphological characteristics of human mast cells
Winner:
IKUNO Tatsuya
Affiliation:
Research Division, Chugai Pharmaceutical Co., Ltd.
Title:
Establishment of human iPS cell-derived hepatocyte panel that defects drug metabolizing enzymes, CYPs, using genome editing technologies for drug toxicity screening
Winner:
DEGUCHI Sayaka
Affiliation:
Graduate School of Pharmaceutical Sciences, Osaka University
Title:
Development of a novel in chemico method for skin sensitization, the amino acid derivative reactivity assay (ADRA)
Winner:
YAMAMOTO Yusuke
Affiliation:
Safety Evaluation Center, Ecology & Quality Management Div., ESG Div., FUJIFILM Corporation
9th 2019
Title:
Application of motion field imaging of human iPS cell-derived cardiomyocytes to cardiac safety assessment
Winner:
ISOBE Takehito
Affiliation:
Research Division, Chugai Pharmaceutical Co., Ltd.
Title:
Chimeric mice with humanized livers demonstrate human-specific hepatotoxicity caused by a therapeutic antibody against TRAIL-receptor 2/death receptor 5
Winner:
NIHIRA Kaito
Affiliation:
Kyowa Hakko Kirin Co., Ltd.
Title:
A long-term culture system based on a collagen vitrigel membrane chamber that supports liver-specific functions of hepatocytes isolated from mice with humanized livers
Winner:
WATARI Ryuji
Affiliation:
Drug Metabolism and Pharmacokinetics Tsukuba, Global Drug Metabolism and Pharmacokinetics, Biopharmaceutical Assessments Core Function Unit, Medicine Development Center, Eisai Co., Ltd., Department of Genomics-Based Drug Discovery, Graduate School of Comprehensive Human Sciences, University of Tsukuba
8th 2018
Title:
Establishment of an novel 3D culture method, air-liquid interface organoid culture and application in toxicity test
Winner:
USUI Tatsuya
Affiliation:
Tokyo University of Agriculture and Technology
Title:
A rapid mitochondrial toxicity assay utilizing rapidly changing cell energy metabolism
Winner:
SANUKI Yosuke
Affiliation:
Asahi Kasei Pharma Co.
7th 2017
Title:
Proposal of a universal in vitro assay for detection of potential risk of severe infusion reaction of monoclonal antibody pharmaceuticals
Winner:
IWATA Yoshika
Affiliation:
Safety Assessment Dept., Chugai Pharmaceutical Co., Ltd.
Title:
Risk assessment of drug-induced liver injury by the expression of immune and inflammation-related factors and microRNAs
Winner:
ODA Shingo
Affiliation:
Nagoya University Graduate School of Medicine
Title:
Establishment of short/medium-term carcinogenesis bioassay by dermal application
Winner:
NUMANO Takamasa
Affiliation:
DIMS Institute of Medical Science, Inc.